Ngokwezibalo ezingaphelele, imikhiqizo ye-FOREGENE ikhonjwe ngephepha le-SCI

Kunezihloko ezingaphezu kuka-3000 sezizonke,

Imikhiqizo yangaphambili iye yathandwa abacwaningi besayensi abaningi ngokwengeziwe ~

I-Stem Cell Therapy

Phakathi nenqubo yokulungiselela amangqamuzana e-stem okwelapha, i-apoptosis ezenzakalelayo yamaseli isebenzisa umphumela we-immunomodulatory ngokukhulula i-phosphatidylserine.

Ishicilelwe ngu: Huaxi Hospital of Sichuan University;Isibhedlela Esihlanganisiwe saseSouthwest Medical University

IF:18.187

Imikhiqizo esetshenzisiwe:Ikhithi Yokuhlukaniswa Yezilwane Ingqikithi ye-RNA

Ukulawulwa kwamasosha omzimba okulamulwa ngamaseli e-mesenchymal stem kuye kwasetshenziswa ekwelapheni izifo zabantu, kodwa indlela yayo eyisisekelo ayizange iqondwe ngokugcwele.Kulesi sihloko, inqubo yokulungiselela amaseli we-stem okwelapha kanye nendlela lapho i-apoptosis ezenzakalelayo yamaseli ikhipha imiphumela yokuzivikela ngokukhishwa kwe-phosphatidylserine.

Ingqikithi yekhithi yokukhipha i-RNA (RE-03011/RE-03014) kusukela ezicutshini zezilwane ze-Fortune isetshenziswe kulesi sihloko ukuze kukhishwe i-RNA ephelele ezicutshini zesibindi zamagundane amodel, bese kwenziwa ukutholwa kwe-RT/qPCR.Ikhwalithi yesamba sokukhishwa kwe-RNA izothinta ngokuqondile ukutholwa kwe-RT/qPCR kokulandelela.Ikhithi yokukhipha yekhwalithi ephezulu ye-RNA ye-Forge Biotech inikeza isiqinisekiso esiqinile sokuhlolwa okungaphansi komfula.

Ucwaningo lwemishini ye-COVID-19

Ukuhlaziywa kwe-plasma multi-omics kuveza izinguquko ze-molecular pathological ku-plasma yezingane ezinesifo esisha se-coronary

Ishicilelwe ngaba: Isibhedlela Sabesifazane Nezingane sase-Guangzhou Medical University;I-Wuhan Institute of Virology, i-Chinese Academy of Sciences;I-Huazhong University of Science and Technology

IF:11.556

Kusetshenziswe imikhiqizo:Ikhithi Yokuzihlukanisa Yeseli Ye-RNA

I-coronavirus entsha ihlaseleka kalula kubo bonke abantu, futhi awukho umehluko omkhulu ngobulili nobudala.Ucwaningo oluningi luye lwabonisa ukuthi uma kuqhathaniswa nabantu abadala, izingane ezinezimpawu ezintsha ze-coronary zinezimpawu ezithambile, kodwa indlela yomehluko ekubonakalisweni komtholampilo phakathi kwezingane nabantu abadala ayikacaci.Ucwaningo lusebenzise ukuhlaziywa kwe-plasma multi-omics ukuze kwembule izinguquko ze-molecular pathological ku-plasma yezingane ezinesifo esisha se-coronary.

Kulesi sihloko, ikhithi yokukhipha i-RNA isiyonke (RE-03111/RE-03113) kumaseli akhulisiwe e-Fortune isetshenziselwa ukukhipha isamba se-RNA kumaseli e-L2 aphathwe nge-SARS-CoV-2 esikhundleni segciwane le-hepatitis legundane, bese kutholwa i-RT/qPCR.Imiphumela ye-omics iphinde yaqinisekiswa.

I-NGO ixhumanisa i-angiogenesis

I-nanographene oxide etholakala ku-Electrochemically yenza kusebenze amaseli ephuzu le-endothelial futhi ikhuthaze i-angiogenesis ngokubopha i-endogenous lysophosphatidic-acid.

Ishicilelwe ngu: Stomatological Hospital of Southern Medical University;I-Institute of Metal Research, i-Chinese Academy of Sciences;Isibhedlela i-Union, i-Tongji Medical College, i-Huazhong University of Science and Technology

IF:14.593

Sebenzisa imikhiqizo:Ikhithi Yokuzihlukanisa Yeseli Ye-RNA

I-graphene oxide inezakhiwo ezinhle zomshini nezomzimba kanye namakhemikhali, futhi inezinhlobonhlobo zezinhlelo zokusebenza kubunjiniyela bezicubu zamathambo.Kodwa-ke, umthelela wayo ku-angiogenesis awukacaci, futhi ubuthi obungase bube khona nabo buphikisana kakhulu.Ucwaningo luthole ukuthi i-electrochemically derived nanographene oxide ingenza kusebenze amaseli wethiphu we-endothelial futhi ikhuthaze i-angiogenesis ngokuhlanganisa ne-endogenous lysophosphatidic acid.

Kulesi sihloko, ikhithi yokukhipha i-RNA isiyonke (RE-03111/RE-03113) kusukela kumaseli akhulisiwe isetshenziswe ukuze kukhishwe i-RNA ephelele kumaseli acutshunguliwe, kulandelwa ukutholwa kwe-RT/qPCR, kanye nezakhi zofuzo ezihlobene zomzila wokusayina we-Wnt zahlaziywa.

Ishadi lokugeleza lokusebenza lekhithi ye-FOREGENE RNA Extraction

Ingaqedela ukukhishwa kwe-RNA yeseli phakathi nemizuzu engu-11

Kusukela yasungulwa, i-FOREGNE ibigxile ekuthuthukisweni kobuchwepheshe obuhlobene nebhayoloji yamangqamuzana, imikhiqizo kanye nezinsizakalo.Bekulokhu kubambelela kumgomo wokuqala wokwenza ukuhlolwa kuphumelele kakhudlwana, kube lula futhi kuphephe, kugcizelele ekhasimendeni kuqala, ukusungula izinto ezintsha, kanye nokuphishekela imikhiqizo encintisanayo, ezinzile nethembekile nezinsizakalo ezingcono!